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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEPCE
All Species:
18.18
Human Site:
Y490
Identified Species:
44.44
UniProt:
Q7L2J0
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L2J0
NP_062552.2
689
74355
Y490
A
R
Q
N
I
R
H
Y
L
S
E
E
L
R
L
Chimpanzee
Pan troglodytes
XP_527836
689
74350
Y490
A
R
Q
N
I
R
H
Y
L
S
E
E
L
R
L
Rhesus Macaque
Macaca mulatta
XP_001104039
689
74134
Y490
A
R
Q
N
I
R
H
Y
L
S
E
E
L
R
L
Dog
Lupus familis
XP_546957
692
75135
Y493
A
R
Q
N
I
R
H
Y
L
S
E
E
L
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8K3A9
666
72032
Y467
A
R
Q
N
I
R
H
Y
L
S
E
E
L
R
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505557
496
54391
R306
S
W
R
A
L
R
M
R
V
A
R
R
G
G
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001921729
629
69161
F431
A
R
Q
N
L
R
H
F
L
S
E
L
Q
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K480
1367
146215
F867
A
R
R
N
L
S
I
F
V
R
I
P
K
E
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9U2R0
378
44095
G186
D
I
D
E
H
L
I
G
V
A
R
K
N
I
R
Sea Urchin
Strong. purpuratus
XP_789930
553
61051
G363
F
K
R
E
W
F
E
G
K
N
C
L
D
I
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
98.4
91.6
N.A.
87
N.A.
N.A.
30.9
N.A.
N.A.
43.5
N.A.
21.8
N.A.
26.4
30.6
Protein Similarity:
100
99.4
98.5
93.5
N.A.
89.6
N.A.
N.A.
37.1
N.A.
N.A.
56.8
N.A.
31.6
N.A.
37.4
45.7
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
6.6
N.A.
N.A.
60
N.A.
20
N.A.
0
0
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
40
N.A.
N.A.
73.3
N.A.
46.6
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
70
0
0
10
0
0
0
0
0
20
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
10
0
10
0
0
0
0
0
0
0
0
0
10
10
0
% D
% Glu:
0
0
0
20
0
0
10
0
0
0
60
50
0
10
10
% E
% Phe:
10
0
0
0
0
10
0
20
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
20
0
0
0
0
10
10
20
% G
% His:
0
0
0
0
10
0
60
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
50
0
20
0
0
0
10
0
0
20
0
% I
% Lys:
0
10
0
0
0
0
0
0
10
0
0
10
10
0
0
% K
% Leu:
0
0
0
0
30
10
0
0
60
0
0
20
50
0
50
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
70
0
0
0
0
0
10
0
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
60
0
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
70
30
0
0
70
0
10
0
10
20
10
0
50
20
% R
% Ser:
10
0
0
0
0
10
0
0
0
60
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
30
0
0
0
0
0
0
% V
% Trp:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _